DMAE and Skin Health

dmae skin health


The skincare industry is continually evolving, discovering new ingredients that promise to combat the signs of aging. Among these, Dimethylaminoethanol, or DMAE, has become a focal point due to its purported skin-firming and anti-aging benefits. In this article we provide an in-depth analysis of DMAE, discussing what it is, its benefits for the skin, potential risks, and how to effectively incorporate it into your skincare routine.


What is DMAE?

dmae cream


Dimethylaminoethanol (DMAE) is a compound found naturally in the brain and is also present in certain fish, including salmon, anchovies, and sardines. It is also chemically synthesized for use in skin care products. In the realm of cosmetics, DMAE is recognized for its potential to improve skin firmness and enhance facial contours. It functions not only as a skin conditioner but also plays a role in reducing the appearance of fine lines and wrinkles.


DMAE for Skin: Mechanism of Action


Dimethylaminoethanol, or DMAE, is gaining recognition in the skincare industry primarily for its role in improving muscle tone and skin firmness through the modulation of the neurotransmitter acetylcholine. (1) Acetylcholine is crucial for muscle contraction and tone, which can directly influence the skin's tightness and overall youthful appearance. The increased production of acetylcholine spurred by DMAE is believed to provide a dual action on the skin: enhancing firmness and reducing the sagging that naturally comes with aging.


The role of DMAE in muscle contraction is significant because it helps improve the underlying muscle tone beneath the skin's surface. This action can lead to a visible reduction in the appearance of wrinkles and sagging. When the facial muscles are firmer and more toned, the skin looks smoother and more defined. This tightening effect is one of the key reasons DMAE is included in many anti-aging skincare formulations.


Beyond its effects on muscle tone, DMAE offers substantial antioxidant properties. These are crucial for protecting the skin against the oxidative stress caused by free radicals. (1Free radicals are unstable molecules that can damage cells, leading to premature aging and a host of skin problems, including wrinkles, dullness, and uneven skin tone. (2) By neutralizing these harmful molecules, DMAE helps protect the skin from environmental stressors such as pollution and UV radiation, which exacerbate the aging process.


Moreover, DMAE is thought to stabilize cell membranes, another critical factor in maintaining skin health and appearance. The stabilization of cell membranes can enhance the skin's ability to retain water and vital nutrients, thereby improving hydration and resilience. This protective barrier not only helps keep the skin hydrated but also shields it from harmful toxins and bacteria, further preventing degradation and aging. (3)


Overall, DMAE addresses several key factors contributing to skin aging, making it a versatile and valuable ingredient in skincare. By improving muscle tone, fighting oxidative stress, and enhancing cellular health, DMAE can significantly impact the skin's appearance, leading to a firmer, smoother, and more vibrant complexion. These multifaceted benefits explain why DMAE is becoming a staple in anti-aging skincare regimens, appealing to those seeking to mitigate the visible signs of aging effectively.


We use DMAE as a primary ingredient in our Glow & Protect Day Cream because of its amazing skin-protective benefits.


What Does DMAE Do for Skin?

dmae skin health


The use of DMAE in skincare revolves around its multiple benefits, which include but are not limited to:


  • Improved Skin Firmness: Regular use of DMAE-infused products can lead to a reduction in skin sagging and an improvement in tone and firmness.
  • Reduction in Fine Lines and Wrinkles: DMAE's potential to boost muscle tone may also help diminish the appearance of fine lines and wrinkles.
  • Enhanced Skin Hydration: Some studies suggest that DMAE may help improve skin hydration, thereby enhancing the skin's overall texture and appearance. (4)
  • Antioxidant ProtectionThe antioxidant properties of DMAE help protect the skin from environmental stressors, potentially preventing premature aging.


Scientific Research Supporting DMAE in Skincare


Several studies have examined the effects of DMAE in skincare, with varying results. A notable study published in the American Journal of Clinical Dermatology observed that topical application of DMAE gel improved the appearance of skin firmness and reduced wrinkles. (5) However, it's important to note that while some research is promising, the dermatological community calls for more extensive studies to fully understand the long-term effects and efficacy of DMAE.


Is DMAE Bad for Your Skin?


Despite its benefits, the safety of DMAE is a topic of debate among skincare experts. Concerns primarily arise regarding the potential for skin irritation and the long-term effects on skin health. Therefore, it is recommended for individuals considering DMAE to:


  1. Consult a Dermatologist: Before starting any new skincare treatment, especially one containing active ingredients like DMAE, consulting with a skincare professional is advisable.
  2. Patch TestingTo minimize the risk of adverse reactions, conducting a patch test prior to regular use is recommended. Here's how to properly conduct a patch test:
    • Select an Area: Choose a small, discreet area of skin for the test, such as behind the ear or on the inner forearm, where the skin is relatively sensitive.
    • Apply a Small Amount: Apply a small amount of the product to the selected area.
    • Wait and Observe: Cover the area with a bandage and wait for at least 24 to 48 hours, during which you should avoid washing the area. Monitor the test spot for any signs of redness, itching, swelling, or other irritation.
    • Evaluate the Results: If no irritation occurs after the waiting period, the product is likely safe for you to use. If you experience any adverse reactions, it's advisable to discontinue use and consult a dermatologist.


This methodical approach helps ensure that you can safely use DMAE-containing products without unexpected or adverse effects, making it a crucial step for anyone with sensitive skin or allergies.


How to Incorporate DMAE into Your Skincare Routine

dmae face cream


Incorporating DMAE into your skincare routine should be done with care to maximize benefits while minimizing potential risks:


  1. Choose the Right Concentration: Products containing DMAE are available in various concentrations. Starting with a lower concentration and gradually increasing based on skin tolerance can help mitigate potential irritation.
  2. Combine with Moisturizers: For those with sensitive skin, combining DMAE with a moisturizer may reduce the risk of irritation.
  3. Morning or Night: DMAE can typically be used either in the morning or at night. If used during the day, it should be followed by sunscreen due to its potential to make the skin more sensitive to sunlight.


Our Glow and Protect Day Cream combines small amounts of high-quality organic ingredients to support skin health, moisturize the skin, and protect the skin from free radical and UV damage.




DMAE is a potent ingredient with promising benefits for those looking to enhance skin firmness and reduce signs of aging. While more research is needed to fully understand its benefits, current research is promising. Still, as with any active ingredient, it is recommended to consult with your healthcare provider before use. With the right DMAE supplement and appropriate application, DMAE can be a valuable addition to a skincare regimen, potentially leading to visibly firmer and more youthful-looking skin.



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