Gut Health

Taking Probiotics With Antibiotics

probiotics and antibiotics

When it comes to treating bacterial infections, antibiotics have been a revolutionary medical intervention. They are powerful medications that help eliminate harmful bacteria from the body, promoting recovery and restoring health.


However, the use of antibiotics can also disrupt the delicate balance of beneficial bacteria in our gut, leading to digestive issues and other potential side effects. To counteract these effects, many people wonder if it is safe and beneficial to take probiotics alongside antibiotics. In this article, we will explore the relationship between antibiotics, gut health, and probiotics, shedding light on when and how to take probiotics with antibiotics.


What Are Antibiotics?



Antibiotics are a class of medications that are used to treat bacterial infections. (1) They are powerful drugs that target and kill bacteria or inhibit their growth, helping the body to fight off infections and restore health. Antibiotics have revolutionized modern medicine, significantly reducing the morbidity and mortality associated with bacterial diseases.


There are various types of antibiotics, each with its own mechanism of action and spectrum of activity against different bacteria. Some common classes of antibiotics include penicillins, cephalosporins, macrolides, tetracyclines, and fluoroquinolones. Each class targets specific types of bacteria or acts against them in different ways.


It is important to note that antibiotic medications are not effective against viral infections. They only work against bacteria, which are living microorganisms that can cause infections in various parts of the body.


Antibiotics can be administered orally in the form of tablets, capsules, or liquids, or they can be given intravenously in more severe cases. The choice of antibiotic depends on factors such as the type of infection, the severity of the condition, the susceptibility of the bacteria, and the patient's individual circumstances.


Understanding Antibiotics and Their Impact on Gut Health

antibiotics and gut health 


Antibiotics are medications that target and destroy bacteria responsible for various infections. While they are undoubtedly valuable in fighting off harmful bacteria, antibiotics do not discriminate between beneficial and harmful bacteria. (2) As a result, the delicate microbial balance in our gut, known as the gut microbiota, can be disrupted. This disruption may lead to unpleasant symptoms such as diarrhea, abdominal discomfort, and compromised immune function. It may also have potentially negative long-term effects on gut health. (2)


What Are Probiotics?



Probiotics, often referred to as "good bacteria," are live microorganisms that offer numerous potential health benefits when consumed in adequate amounts. (3) These beneficial bacteria can help restore and maintain the balance of the gut microbiota, which refers to the complex community of microorganisms residing in our gastrointestinal tract. The gut microbiota is composed of trillions of bacteria, both beneficial and potentially harmful, that interact with our bodies in various ways. (4)


Probiotics have been shown to support digestion, improve immune system, and support overall gut health. (3) They can be found in certain foods like yogurt, sauerkraut, and kefir, as well as in supplement form.


The most common and well-researched types of probiotics belong to the Lactobacillus genus and Bifidobacterium genus, although other strains and species may also have probiotic properties. Each probiotic strain has unique characteristics and potential health benefits.


Can You Take Probiotics with Antibiotics?


Yes, you can take probiotics with antibiotics. Although antibiotics can potentially diminish the effectiveness of probiotics by killing some of the supplemented bacteria, research suggests that taking probiotics with antibiotics can still offer benefits. (5


Probiotics help protect the gut during a course of antibiotics by replenishing the beneficial bacteria that are often depleted by the medication. Additionally, they may help reduce the risk of antibiotic-associated side effects, such as antibiotic-associated diarrhea.


Why Don't Doctors Prescribe Probiotics with Antibiotics?

doctor prescription


While probiotics have shown promise in supporting gut health during antibiotic use, the prescription of probiotics alongside antibiotics is not yet a common medical practice. The primary reason is the variability of bacterial strains and dosages in available probiotic products. The specific strains and doses that would be most effective for each individual and each antibiotic are not yet well-defined. Consequently, doctors may be hesitant to recommend specific probiotics due to the lack of standardized guidelines and evidence for their effectiveness.


Should You Take Probiotics with Antibiotics?


The decision to take probiotics with antibiotics is ultimately a personal one. If you are considering taking probiotics during antibiotic treatment, it is recommended to consult with your healthcare provider, who can provide guidance based on your unique circumstances.


That being said, taking probiotics alongside antibiotics may offer several potential benefits, particularly in supporting gut health during antibiotic treatment. Probiotics can help counteract the negative effects of antibiotics on the gut microbiota, which is the community of microorganisms in our digestive system. (5)


Antibiotics, while crucial for eliminating harmful bacteria, can also disrupt the balance of beneficial bacteria in the gut. This disruption may lead to digestive issues, such as diarrhea, as well as compromised immune function.


By taking probiotics during antibiotic treatment, you can introduce beneficial bacteria into your gut, helping to restore and maintain a healthy microbial balance. While some studies have shown that the effectiveness of probiotics may be reduced when taken alongside antibiotics, research suggests that the benefits of taking probiotics outweigh any potential drawbacks. Even if some of the supplemented bacteria are affected by antibiotics, probiotics can still contribute to overall gut health by stimulating the growth and activity of the existing beneficial bacteria.


It is important to note that not all probiotics are the same, and their efficacy can vary depending on the strains and dosages used. To maximize the potential benefits, it is advisable to select probiotic products that contain well-documented strains, such as Lactobacillus acidophilusBifidobacterium bifidum, or Saccharomyces boulardii. These strains have shown effectiveness in supporting gut health during antibiotic treatment.


It is also recommended to supplement with a Multi-Strain Probiotic, as the diversity of strains may help to ensure more biodiversity in the guts—ultimately resulting in a healthier gut microbiome.


How to Take Probiotics with Antibiotics

probiotics with antibiotics


To maximize the potential benefits of taking probiotics with antibiotics, it is important to follow some best practices:


1.    Timing: Take your probiotic supplement at least two hours apart from your antibiotic dose. This interval helps reduce the potential interaction between antibiotics and probiotics.

2.    Strain Selection: Look for probiotic products that contain well-documented strains, such as Lactobacillus acidophilus, Bifidobacterium bifidum, or Saccharomyces boulardii. These strains have shown efficacy in supporting gut health.

3.    Dosage: Follow the dosage instructions provided with the probiotic product or consult your healthcare provider for personalized recommendations.

4.    Duration: Continue taking probiotics for a few weeks after completing your antibiotic course to help restore and maintain healthy gut microbiota.




Taking probiotics with antibiotics can be a valuable strategy to support gut health during and after antibiotic treatment. While antibiotics are essential for fighting infections, they can disrupt the balance of beneficial bacteria in the gut, leading to potential digestive issues. Probiotics, with their ability to restore and maintain healthy gut microbiota, can help mitigate these effects.


While there is no definitive consensus on prescribing probiotics with antibiotics, taking probiotics alongside antibiotic treatment can potentially benefit gut health. By replenishing the beneficial bacteria, probiotics can help minimize disruptions caused by antibiotics. However, it is always advisable to consult with a healthcare provider to determine the best approach based on individual circumstances. 


Taking probiotics with antibiotics, when done correctly, can serve as a proactive step towards supporting gut health during and after antibiotic therapy.



Products mentioned in this post

Multi-Strain Probiotic Complex

Multi-Strain Probiotic Complex


Gut Health, Digestive Health, Mood

True Health Starts with Feeding the Body

Subscribe to receive updates, access to exclusive deals, and more.